Studier med NGICG-involvering

NORWAIT-Studien

taTME -audit 

Internasjonale studier på GI cancer

Clinical trials.gov - Norway - Colon cancer

 

ASAC studien

Randomisert studie som ser på nyten av adjuvant acetylsalisylsyre etter leverkirurgi for metastaser fra kolorektal kreft

https://www.asac.no

NORPACT-1 studien

Randomisering mellom neoadjuvant kjemoterapi eller direkte kirurgi for pasienter med operabel pankreaskreft. Studien har stoppet inklusjon, resultater forventes tidligst 2022/23.

 

https://clinicaltrials.gov/ct2/show/NCT02919787

https://pubmed.ncbi.nlm.nih.gov/28841916/

UI DESIGN

ExCalibur study 1-3

The Excalibur-project consists of 3 randomized control trials, Excalibur 1-3, and is conducted at Oslo University Hospital, Department of HPB-surgery. The project aims to increase overall survival for patients with extensive colorectal livermetastasis and insufficient response to 1st line chemotherapy. This group have a dismal prognosis, with current OS at 10-14 months. 

 

Excalibur 1 will randomize eligible patients to 1 of 3 treatment-arms. These arms will be HAI, transplantation or 2nd line chemotherapy.

 

Excalibur 2 will be similar to Excalibur 1, but without the transplantation arm, allowing for somewhat broader inclusion criteria.

 

Excalibur 3 is completely separate from 1 and 2, and is a randomized control randomizing patients with extensive colorectal livermetastisis, progression on 1st line chemotherapy and resectable disease, to either surgery and 2nd line chemotherapy or just 2nd line chemotherapy with primary endpoint being overall survival at 2 years.

 

 

se mer info på:

 

https://www.excaliburstudy.com